In a mixing bowl, mix graham cracker crumbs and melted Pumpkin Spice Butter until completely combined. Press mixture into the bottom of a cheesecake pan, creating a ridge along the outside. Chill for 1 hour.
Meanwhile, in a mixing bowl, combine cream cheese, whipping cream, powdered sugar, pumpkin, pumpkin pie spice, and vanilla. Mix until combined, and light and fluffy.
Pour filling into the chilled graham cracker crust.